Heart
ApoB helps transport lipids throughout the bloodstream which is vital to the health of cardiovascular function. Along with other lipid tests ApoB is a powerful risk marker for cardiovascular disease.
Measures the ratio of total cholesterol levels to high-density lipoprotein cholesterol (HDL).
HDL is part of a comprehensive lipid panel, an essential risk assessment for heart disease. There are two types of cholesterol: high-density lipoprotein (HDL) and low-density lipoprotein (LDL). Think of the H as healthy, helpful, heart-supporting cholesterol that helps reduce plaque buildup.
Large HDL particles in the blood are protective; having a higher amount is beneficial because they help reduce the risk of cardiovascular disease.
hs-CRP is revelatory in one's overall health as it relates to the risk of inflammation-related diseases. Chronic inflammation is linked to every major disease: heart disease (even before symptoms occur), type 2 diabetes, cancer, high blood pressure, Alzheimer’s, depression, all autoimmune diseases, and severe allergic reactions like asthma.
This test is a risk marker for cardiovascular diseases. LDL is responsible for carrying cholesterol to cells. However, despite its good intentions, LDL is known as the “bad” cholesterol because, when levels are too high, it can cause the formation of plaque buildup in the arteries.
Measures the amount of medium LDL particles in the blood. Elevated medium LDL levels are associated with an increased risk of atherosclerosis and cardiovascular disease.
Measures the number of LDL particles, which are the carriers of cholesterol. Too many LDL particles can lead to plaque buildup in arteries, increasing the risk of heart disease and stroke.
Assesses the risk of cardiovascular disease based on cholesterol health, either Pattern A or Pattern B.
Refers to the most common or average size of LDL particles in your blood. This is important because smaller LDL particles are more likely to contribute to plaque buildup in arteries, increasing the risk of cardiovascular disease.
Small LDL particles in the blood are harmful, as elevated levels are linked to a higher risk of atherosclerosis and cardiovascular disease.
About 50% of people who suffer heart attacks have a normal cholesterol level. Considering this, many cardiologists believe Lp(a) to be a major driver of cardiac events. This invaluable test is used by specialists but is not yet widely adopted in primary care. Lp(a) is a genetic marker that determines risk, particularly for those with symptoms or a family history of cardiovascular disease. Lipoproteins are made of lipids (fats) and proteins (energy) and are referred to as "sticky proteins."
Measures cholesterol that is not HDL. This is a risk marker for dyslipidemia, cardiovascular disease, and metabolic syndrome.
Total cholesterol numbers are part of a risk assessment for heart disease. Too much cholesterol in the blood can damage arteries and blood vessels and elevate the risk for stroke, heart attack, and heart disease. Cholesterol is a fatty substance produced by the liver to help with thousands of bodily functions, such as building cells, promoting hormone and brain function, and synthesizing vitamin D.
The ratio of triglycerides to HDL measures risk for heart disease. Triglycerides are the most common type of fat in the body that stores excess energy from one's diet. An accumulation of triglycerides means there is too much fat in the blood and may indicate higher risk of a cardiac event.
A key protein component of HDL (the "good cholesterol") Apolipoprotein A1 helps transport cholesterol out of arteries and plays a protective role against cardiovascular disease. *This add-on test is available for an additional cost and is not included in the $499 membership.
Apolipoprotein C1 regulates triglyceride metabolism and is a marker for lipid imbalances that can contribute to cardiovascular disease. *This add-on test is available for an additional cost and is not included in the $499 membership.
This test measures Apolipoprotein C2 a protein involved in triglyceride regulation and energy metabolism which can impact cardiovascular and metabolic health. *This add-on test is available for an additional cost and is not included in the $499 membership.
Apolipoprotein C3 inhibits the breakdown of triglycerides and is associated with an increased risk of atherosclerosis (artery plaque buildup) and cardiovascular disease. *This add-on test is available for an additional cost and is not included in the $499 membership.
Apolipoprotein C4 plays a role in lipid transport and metabolism and abnormalities may be linked to cardiovascular risk. *This add-on test is available for an additional cost and is not included in the $499 membership.
The estimated glomerular filtration rate (eGFR) is a key measure of kidney function essential for identifying changes that may impact cardiovascular and metabolic health. Testing supports early intervention in kidney-related issues.
Cystatin C is a marker of kidney function and an important indicator of cardiovascular health as impaired kidney function is closely linked to increased strain on the heart and blood vessels. Elevated levels can signal changes in kidney performance and metabolic function helping to identify risks early. *This add-on test is available for an additional cost and is not included in the $499 membership.
Fibrinogen is a key protein involved in blood clotting and inflammation. Elevated levels are associated with an increased risk of heart attacks strokes and other cardiovascular events. *This add-on test is available for an additional cost and is not included in the $499 membership.
Evaluates the functional quality of HDL particles focusing on their ability to remove excess cholesterol and reduce plaque buildup in arteries. Unlike traditional HDL measurements this score looks at how effectively HDL particles perform their protective roles offering a more precise assessment of cardiovascular health. *This add-on test is available for an additional cost and is not included in the $499 membership.
Measures HDL cholesterol efflux capacity (CEC) which shows how effectively HDL removes cholesterol from cells and transports it to the liver for processing and elimination. This process is a key function of HDL in protecting against heart disease as it helps reduce cholesterol buildup in blood vessels. *This add-on test is available for an additional cost and is not included in the $499 membership.
Measures the activity of lipoprotein-associated phospholipase A2 (Lp-PLA2) an enzyme produced by inflamed blood vessel walls. It helps assess the presence of vascular inflammation that can increase the risk of heart attack or stroke. *This add-on test is available for an additional cost and is not included in the $499 membership.
MPO is an enzyme involved in immune responses and inflammation in blood vessels. Elevated levels may signal oxidative stress impacting blood vessel health. Testing MPO can help identify early signs of vascular inflammation and guide strategies to support heart health and prevent future cardiovascular issues. *This add-on test is available for an additional cost and is not included in the $499 membership.
Oxidized LDL is a harmful form of cholesterol altered by oxidative stress making it more likely to stick to artery walls and contribute to plaque buildup. This can trigger inflammation and accelerate atherosclerosis which increases the risk of cardiovascular disease and related complications. *This add-on test is available for an additional cost and is not included in the $499 membership.
TMAO is a compound produced in the gut that is linked to cardiovascular risk. High levels are associated with plaque buildup in arteries and heart disease offering insights into how gut health is impacting cardiovascular function. *This add-on test is available for an additional cost and is not included in the $499 membership.
This test identifies genetic markers associated with atrial fibrillation (AFib), a common heart rhythm disorder that increases the risk of stroke and heart failure. Knowing your risk can guide preventive care. *This add-on test is available for an additional cost and is not included in the $499 membership.
Known as the "heart attack gene," this test identifies genetic variations associated with a higher likelihood of developing coronary artery disease. It helps evaluate your inherited risk for heart disease and guides preventive care strategies. *This add-on test is available for an additional cost and is not included in the $499 membership.
Looks at genetic variations that affect how your body responds to aspirin, particularly in those with high lipoprotein(a) (Lp(a)) levels, a genetic risk factor for heart attack and stroke. This test helps determine whether low-dose aspirin therapy may be effective in reducing cardiovascular risks. *This add-on test is available for an additional cost and is not included in the $499 membership.
This test analyzes genetic variations in the MTHFR (methylenetetrahydrofolate reductase) gene, which plays an important role in processing folate (vitamin B9) and regulating homocysteine, a substance linked to heart and brain health. Variants in this gene can affect cardiovascular health, energy production, reproduction, and neurological function. *This add-on test is available for an additional cost and is not included in the $499 membership.
The ratio of Apolipoprotein B (found in "bad" cholesterol particles like LDL) to Apolipoprotein A1 (found in "good" cholesterol particles like HDL) evaluates the balance between harmful and protective cholesterol particles providing a risk assessment for conditions like atherosclerosis heart attack and stroke. A higher ratio typically indicates a greater risk of cardiovascular disease. *This add-on test is available for an additional cost and is not included in the $499 membership.
The average physical tests only 19 biomarkers.