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Why it matters?
Your heart will beat roughly 2.5 billion times over your lifetime, tirelessly pumping blood through 60,000 miles of vessels to deliver life-sustaining oxygen and nutrients throughout the body. Testing key markers–lipoprotein (a) ApoB, the size and quantity of lipids, and inflammation –provides a window into the health of this crucial system. These biomarkers can detect early cardiovascular changes, allowing for proactive steps to maintain strong heart function and healthy circulation through targeted lifestyle and dietary approaches.
Apolipoprotein B (ApoB)
2x
Indicates biomarkers that are tested twice per year.
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Total Cholesterol / HDL Ratio
2x
Indicates biomarkers that are tested twice per year.
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HDL Cholesterol
2x
Indicates biomarkers that are tested twice per year.
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HDL Large
2x
Indicates biomarkers that are tested twice per year.
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High-Sensitivity C-Reactive Protein (hs-CRP)
2x
Indicates biomarkers that are tested twice per year.
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LDL Cholesterol
2x
Indicates biomarkers that are tested twice per year.
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LDL Medium
2x
Indicates biomarkers that are tested twice per year.
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LDL Particle Number
2x
Indicates biomarkers that are tested twice per year.
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LDL Pattern
2x
Indicates biomarkers that are tested twice per year.
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LDL Peak Size
2x
Indicates biomarkers that are tested twice per year.
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LDL Small
2x
Indicates biomarkers that are tested twice per year.
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Lipoprotein (a)
2x
Indicates biomarkers that are tested twice per year.
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Non-HDL Cholesterol
2x
Indicates biomarkers that are tested twice per year.
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Total Cholesterol
2x
Indicates biomarkers that are tested twice per year.
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Triglycerides
2x
Indicates biomarkers that are tested twice per year.
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Apolipoprotein A1
2x
Indicates biomarkers that are tested twice per year.
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Apolipoprotein C1
2x
Indicates biomarkers that are tested twice per year.
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Apolipoprotein C2
2x
Indicates biomarkers that are tested twice per year.
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Apolipoprotein C3
2x
Indicates biomarkers that are tested twice per year.
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Apolipoprotein C4
2x
Indicates biomarkers that are tested twice per year.
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Estimated Glomerular Filtration Rate
2x
Indicates biomarkers that are tested twice per year.
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Cystatin C
2x
Indicates biomarkers that are tested twice per year.
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Fibrinogen Antigen, Nephelometry
2x
Indicates biomarkers that are tested twice per year.
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HDLfx pCAD Score
2x
Indicates biomarkers that are tested twice per year.
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HDLfx pCEC
2x
Indicates biomarkers that are tested twice per year.
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Lp-PLA2 Activity
2x
Indicates biomarkers that are tested twice per year.
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Myeloperoxidase
2x
Indicates biomarkers that are tested twice per year.
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Oxidized LDL
2x
Indicates biomarkers that are tested twice per year.
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Trimethylamine N-Oxide
2x
Indicates biomarkers that are tested twice per year.
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4q25-Atrial Fibrillation Risk
2x
Indicates biomarkers that are tested twice per year.
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9p21 Genotype
2x
Indicates biomarkers that are tested twice per year.
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LPA Aspirin Genotype
2x
Indicates biomarkers that are tested twice per year.
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MTHFR, DNA
2x
Indicates biomarkers that are tested twice per year.
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Apolipoprotein B/Apolipoprotein A1 Ratio
2x
Indicates biomarkers that are tested twice per year.
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The average physical tests only 19 biomarkers.

Function includes over 100 tests to give you the complete picture of your health.
Apolipoprotein B (ApoB)
2x
Indicates biomarkers that are tested twice per year.
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Newly added test
Anytime Tests
Hormone & Metabolic Health
Longevity / Healthspan
The Yearly
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Apolipoprotein B (ApoB)

ApoB helps transport lipids throughout the bloodstream which is vital to the health of cardiovascular function. Along with other lipid tests ApoB is a powerful risk marker for cardiovascular disease.

Total Cholesterol / HDL Ratio
2x
Indicates biomarkers that are tested twice per year.
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The Yearly
Hormone & Metabolic Health
Longevity / Healthspan
The Mid Year
Total Cholesterol / HDL Ratio

Measures the ratio of total cholesterol levels to high-density lipoprotein cholesterol (HDL).

HDL Cholesterol
2x
Indicates biomarkers that are tested twice per year.
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The Mid Year
HDL Cholesterol

HDL is part of a comprehensive lipid panel, an essential risk assessment for heart disease. There are two types of cholesterol: high-density lipoprotein (HDL) and low-density lipoprotein (LDL). Think of the H as healthy, helpful, heart-supporting cholesterol that helps reduce plaque buildup.

HDL Large
2x
Indicates biomarkers that are tested twice per year.
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Longevity / Healthspan
HDL Large

Large HDL particles in the blood are protective; having a higher amount is beneficial because they help reduce the risk of cardiovascular disease.

High-Sensitivity C-Reactive Protein (hs-CRP)
2x
Indicates biomarkers that are tested twice per year.
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The Mid Year
High-Sensitivity C-Reactive Protein (hs-CRP)

hs-CRP is revelatory in one's overall health as it relates to the risk of inflammation-related diseases. Chronic inflammation is linked to every major disease: heart disease (even before symptoms occur), type 2 diabetes, cancer, high blood pressure, Alzheimer’s, depression, all autoimmune diseases, and severe allergic reactions like asthma.

LDL Cholesterol
2x
Indicates biomarkers that are tested twice per year.
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Hormone & Metabolic Health
Longevity / Healthspan
LDL Cholesterol

This test is a risk marker for cardiovascular diseases. LDL is responsible for carrying cholesterol to cells. However, despite its good intentions, LDL is known as the “bad” cholesterol because, when levels are too high, it can cause the formation of plaque buildup in the arteries.

LDL Medium
2x
Indicates biomarkers that are tested twice per year.
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LDL Medium

Measures the amount of medium LDL particles in the blood. Elevated medium LDL levels are associated with an increased risk of atherosclerosis and cardiovascular disease.

LDL Particle Number
2x
Indicates biomarkers that are tested twice per year.
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LDL Particle Number

Measures the number of LDL particles, which are the carriers of cholesterol. Too many LDL particles can lead to plaque buildup in arteries, increasing the risk of heart disease and stroke.

LDL Pattern
2x
Indicates biomarkers that are tested twice per year.
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LDL Pattern

Assesses the risk of cardiovascular disease based on cholesterol health, either Pattern A or Pattern B.

LDL Peak Size
2x
Indicates biomarkers that are tested twice per year.
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LDL Peak Size

Refers to the most common or average size of LDL particles in your blood. This is important because smaller LDL particles are more likely to contribute to plaque buildup in arteries, increasing the risk of cardiovascular disease.

LDL Small
2x
Indicates biomarkers that are tested twice per year.
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LDL Small

Small LDL particles in the blood are harmful, as elevated levels are linked to a higher risk of atherosclerosis and cardiovascular disease.

Lipoprotein (a)
2x
Indicates biomarkers that are tested twice per year.
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Lipoprotein (a)

About 50% of people who suffer heart attacks have a normal cholesterol level. Considering this, many cardiologists believe Lp(a) to be a major driver of cardiac events. This invaluable test is used by specialists but is not yet widely adopted in primary care. Lp(a) is a genetic marker that determines risk, particularly for those with symptoms or a family history of cardiovascular disease. Lipoproteins are made of lipids (fats) and proteins (energy) and are referred to as "sticky proteins."

Non-HDL Cholesterol
2x
Indicates biomarkers that are tested twice per year.
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Non-HDL Cholesterol

Measures cholesterol that is not HDL. This is a risk marker for dyslipidemia, cardiovascular disease, and metabolic syndrome.

Total Cholesterol
2x
Indicates biomarkers that are tested twice per year.
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Total Cholesterol

Total cholesterol numbers are part of a risk assessment for heart disease. Too much cholesterol in the blood can damage arteries and blood vessels and elevate the risk for stroke, heart attack, and heart disease. Cholesterol is a fatty substance produced by the liver to help with thousands of bodily functions, such as building cells, promoting hormone and brain function, and synthesizing vitamin D.

Triglycerides
2x
Indicates biomarkers that are tested twice per year.
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Triglycerides

The ratio of triglycerides to HDL measures risk for heart disease. Triglycerides are the most common type of fat in the body that stores excess energy from one's diet. An accumulation of triglycerides means there is too much fat in the blood and may indicate higher risk of a cardiac event.

Apolipoprotein A1
2x
Indicates biomarkers that are tested twice per year.
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Hormone & Metabolic Health
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Apolipoprotein A1

A key protein component of HDL (the "good cholesterol") Apolipoprotein A1 helps transport cholesterol out of arteries and plays a protective role against cardiovascular disease. *This add-on test is available for an additional cost and is not included in the $499 membership.

Apolipoprotein C1
2x
Indicates biomarkers that are tested twice per year.
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Apolipoprotein C1

Apolipoprotein C1 regulates triglyceride metabolism and is a marker for lipid imbalances that can contribute to cardiovascular disease. *This add-on test is available for an additional cost and is not included in the $499 membership.

Apolipoprotein C2
2x
Indicates biomarkers that are tested twice per year.
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Apolipoprotein C2

This test measures Apolipoprotein C2 a protein involved in triglyceride regulation and energy metabolism which can impact cardiovascular and metabolic health. *This add-on test is available for an additional cost and is not included in the $499 membership.

Apolipoprotein C3
2x
Indicates biomarkers that are tested twice per year.
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Apolipoprotein C3

Apolipoprotein C3 inhibits the breakdown of triglycerides and is associated with an increased risk of atherosclerosis (artery plaque buildup) and cardiovascular disease. *This add-on test is available for an additional cost and is not included in the $499 membership.

Apolipoprotein C4
2x
Indicates biomarkers that are tested twice per year.
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Apolipoprotein C4

Apolipoprotein C4 plays a role in lipid transport and metabolism and abnormalities may be linked to cardiovascular risk. *This add-on test is available for an additional cost and is not included in the $499 membership.

Estimated Glomerular Filtration Rate
2x
Indicates biomarkers that are tested twice per year.
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Estimated Glomerular Filtration Rate

The estimated glomerular filtration rate (eGFR) is a key measure of kidney function essential for identifying changes that may impact cardiovascular and metabolic health. Testing supports early intervention in kidney-related issues.

Cystatin C
2x
Indicates biomarkers that are tested twice per year.
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Cystatin C

Cystatin C is a marker of kidney function and an important indicator of cardiovascular health as impaired kidney function is closely linked to increased strain on the heart and blood vessels. Elevated levels can signal changes in kidney performance and metabolic function helping to identify risks early. *This add-on test is available for an additional cost and is not included in the $499 membership.

Fibrinogen Antigen, Nephelometry
2x
Indicates biomarkers that are tested twice per year.
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Longevity / Healthspan
Fibrinogen Antigen, Nephelometry

Fibrinogen is a key protein involved in blood clotting and inflammation. Elevated levels are associated with an increased risk of heart attacks strokes and other cardiovascular events. *This add-on test is available for an additional cost and is not included in the $499 membership.

HDLfx pCAD Score
2x
Indicates biomarkers that are tested twice per year.
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Hormone & Metabolic Health
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HDLfx pCAD Score

Evaluates the functional quality of HDL particles focusing on their ability to remove excess cholesterol and reduce plaque buildup in arteries. Unlike traditional HDL measurements this score looks at how effectively HDL particles perform their protective roles offering a more precise assessment of cardiovascular health. *This add-on test is available for an additional cost and is not included in the $499 membership.

HDLfx pCEC
2x
Indicates biomarkers that are tested twice per year.
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HDLfx pCEC

Measures HDL cholesterol efflux capacity (CEC) which shows how effectively HDL removes cholesterol from cells and transports it to the liver for processing and elimination. This process is a key function of HDL in protecting against heart disease as it helps reduce cholesterol buildup in blood vessels. *This add-on test is available for an additional cost and is not included in the $499 membership.

Lp-PLA2 Activity
2x
Indicates biomarkers that are tested twice per year.
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Longevity / Healthspan
Lp-PLA2 Activity

Measures the activity of lipoprotein-associated phospholipase A2 (Lp-PLA2) an enzyme produced by inflamed blood vessel walls. It helps assess the presence of vascular inflammation that can increase the risk of heart attack or stroke. *This add-on test is available for an additional cost and is not included in the $499 membership.

Myeloperoxidase
2x
Indicates biomarkers that are tested twice per year.
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Longevity / Healthspan
Myeloperoxidase

MPO is an enzyme involved in immune responses and inflammation in blood vessels. Elevated levels may signal oxidative stress impacting blood vessel health. Testing MPO can help identify early signs of vascular inflammation and guide strategies to support heart health and prevent future cardiovascular issues. *This add-on test is available for an additional cost and is not included in the $499 membership.

Oxidized LDL
2x
Indicates biomarkers that are tested twice per year.
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Oxidized LDL

Oxidized LDL is a harmful form of cholesterol altered by oxidative stress making it more likely to stick to artery walls and contribute to plaque buildup. This can trigger inflammation and accelerate atherosclerosis which increases the risk of cardiovascular disease and related complications. *This add-on test is available for an additional cost and is not included in the $499 membership.

Trimethylamine N-Oxide
2x
Indicates biomarkers that are tested twice per year.
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Trimethylamine N-Oxide

TMAO is a compound produced in the gut that is linked to cardiovascular risk. High levels are associated with plaque buildup in arteries and heart disease offering insights into how gut health is impacting cardiovascular function. *This add-on test is available for an additional cost and is not included in the $499 membership.

4q25-Atrial Fibrillation Risk
2x
Indicates biomarkers that are tested twice per year.
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4q25-Atrial Fibrillation Risk

This test identifies genetic markers associated with atrial fibrillation (AFib), a common heart rhythm disorder that increases the risk of stroke and heart failure. Knowing your risk can guide preventive care. *This add-on test is available for an additional cost and is not included in the $499 membership.

9p21 Genotype
2x
Indicates biomarkers that are tested twice per year.
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9p21 Genotype

Known as the "heart attack gene," this test identifies genetic variations associated with a higher likelihood of developing coronary artery disease. It helps evaluate your inherited risk for heart disease and guides preventive care strategies. *This add-on test is available for an additional cost and is not included in the $499 membership.

LPA Aspirin Genotype
2x
Indicates biomarkers that are tested twice per year.
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LPA Aspirin Genotype

Looks at genetic variations that affect how your body responds to aspirin, particularly in those with high lipoprotein(a) (Lp(a)) levels, a genetic risk factor for heart attack and stroke. This test helps determine whether low-dose aspirin therapy may be effective in reducing cardiovascular risks. *This add-on test is available for an additional cost and is not included in the $499 membership.

MTHFR, DNA
2x
Indicates biomarkers that are tested twice per year.
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Fertility / Family Planning
Hormone & Metabolic Health
Energy
MTHFR, DNA

This test analyzes genetic variations in the MTHFR (methylenetetrahydrofolate reductase) gene, which plays an important role in processing folate (vitamin B9) and regulating homocysteine, a substance linked to heart and brain health. Variants in this gene can affect cardiovascular health, energy production, reproduction, and neurological function. *This add-on test is available for an additional cost and is not included in the $499 membership.

Apolipoprotein B/Apolipoprotein A1 Ratio
2x
Indicates biomarkers that are tested twice per year.
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Hormone & Metabolic Health
Longevity / Healthspan
Apolipoprotein B/Apolipoprotein A1 Ratio

The ratio of Apolipoprotein B (found in "bad" cholesterol particles like LDL) to Apolipoprotein A1 (found in "good" cholesterol particles like HDL) evaluates the balance between harmful and protective cholesterol particles providing a risk assessment for conditions like atherosclerosis heart attack and stroke. A higher ratio typically indicates a greater risk of cardiovascular disease. *This add-on test is available for an additional cost and is not included in the $499 membership.

Heart